Advances in the Application of Autologous Platelet Concentrate in the Field of Gynecology
摘要: 自体富血小板浓缩物是通过抽取人体或动物血液经过离心获得的血小板浓缩物,主要包括第一代血小板浓缩物富血小板血浆(PRP)及第二代血小板浓缩物富血小板纤维蛋白(PRF)。因其促进伤口愈合及组织修复的作用,被广泛运用于口腔种植、骨缺损修复、烧伤整形等领域。近年来,自体富血小板浓缩物开始运用于改善卵巢功能、促进子宫内膜增生修复、治疗宫颈及外阴相关病变,并取得了显著疗效,但目前缺乏对PRP、PRF在妇科领域研究成果的有效整合。本文系统、全面的梳理了自体富血小板浓缩物的制备、生物学特性以及在妇科多种疾病中的应用,以期能为临床医生提供妇科相关疾病新的治疗思路,并为自体富血小板浓缩物研究应用的深入开展提供借鉴。
Abstract: Autologous platelet concentrate(APC)is a platelet concentrate obtained by centrifugation of human or animal blood,mainly includes first-generation platelet concentrate platelet-rich plasma(PRP)and second-generation platelet concentrate platelet-rich fibrin(PRF),which is widely applied in varies fields such as dental implants,bone defect repairing and burn plastic surgery because of its role in wound healing and tissue repair. In recent years,autologous platelet concentrate has been applied to improve ovarian function,promote the repair of endometrial hyperplasia,treat cervical and vulvo-related lesions,and has achieved significant efficacy. However,there is a lack of effective integration of PRP and PRF research results in the field of gynecology. This paper systematically and comprehensively review the preparation,biological properties and applications in various gynecological diseases,in order to to provide clinicians with new treatment ideas for gynecological diseases and reference for the further application of APC.
[V1] | 2023-05-29 11:02:42 | ChinaXiv:202305.00229V1 | 下载全文 |
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