• Spatiotemporal dynamic and drivers of ecological environmental quality on the Chinese Loess Plateau: Insights from kRSEI model and climate-human interaction analysis

    分类: 地球科学 >> 地理学 提交时间: 2025-07-17 合作期刊: 《干旱区科学》

    摘要: The Loess Plateau (LP), one of the most ecologically fragile regions in China, is affected by severe soil erosion and environmental degradation. Despite large-scale ecological restoration efforts made by Chinese government in recent years, the region continues to face significant ecological challenges due to the combined impact of climate change and human activities. In this context, we developed a kernal Remote Sensing Ecological Index (kRSEI) using Moderate Resolution Imaging Spectroradiometer (MODIS) products on the Google Earth Engine (GEE) platform to analyze the spatiotemporal patterns and trends in ecological environmental quality (EEQ) across the LP from 2000 to 2022 and project future trajectories. Then, we applied partial correlation analysis and multivariate regression residual analysis to further quantify the relative contributions of climate change and human activities to EEQ. During the study period, the kRSEI values exhibited significant spatial heterogeneity, with a stepwise degradation pattern in the southeast to northwest across the LP. The maximum (0.51) and minimum (0.46) values of the kRSEI were observed in 2007 and 2021, respectively. Trend analyses revealed a decline in EEQ across the LP. Hurst exponent analysis predicted a trend of weak anti-persistent development in most of the plateau areas in the future. A positive correlation was identified between kRSEI and precipitation, particularly in the central and western regions; although, improvements were limited by a precipitation threshold of 837.66 mm/a. A moderate increase in temperature was shown to potentially benefit the ecological environment within a certain range; however, temperature of –1.00°C–7.95°C often had a negative impact on the ecosystem. Climate change and human activities jointly influenced 65.78% of LP area on EEQ, primarily having a negative impact. In terms of contribution, human activities played a dominant role in driving changes in EEQ across the plateau. These findings provide crucial insights for accurately assessing the ecological state of the LP and suggest the design of future restoration strategies.

  • Self-Assembly of Ferritin Nanoparticles into an Enzyme Nanocomposite with Tunable Size for Ultrasensitive Immunoassay

    分类: 生物学 >> 生物物理学 提交时间: 2016-05-12

    摘要: The self-assembly of nanoparticles into larger superstructures is a powerful strategy to develop novel functional nanomaterials, as these superstructures display collective properties that are different to those displayed by individual nanoparticles or bulk samples. However, there are increasing bottlenecks in terms of size control and multifunctionalization of nanoparticle assemblies. In this study, we developed a self-assembly strategy for construction of multifunctional nanoparticle assemblies of tunable size, through rational regulation of the number of self-assembling interaction sites on each nanoparticle. As proof-of-principle, a size-controlled enzyme nanocomposite (ENC) was constructed by self-assembly of streptavidin-labeled horseradish peroxidase (SA-HRP) and autobiotinylated ferritin nanoparticles (bFNP). Our ENC integrates a large number of enzyme molecules, together with a streptavidin-coated surface, allowing for a drastic increase in enzymatic signal when the SA is bound to a biotinylated target molecule. As result, a 10000-fold increase in sensitivity over conventional enzyme-linked immunosorbent assays (ELISA) methods was achieved in a cardiac troponin immunoassay. Our method presented here should provide a feasible approach for constructing elaborate multifunctional superstructures of tunable size useful for a broad range of biomedical applications.