分类: 医学、药学 >> 临床医学 提交时间: 2023-11-10 合作期刊: 《中国全科医学》
摘要: none
分类: 生物学 >> 生态学 提交时间: 2023-05-11 合作期刊: 《干旱区科学》
摘要:Ecosystem responses to climate change, particularly in arid environments, is an understudied topic. This study conducted a spatial analysis of ecosystem responses to short-term variability in temperature, precipitation, and solar radiation in the Qilian Mountains National Park, an arid mountainous region in Northwest China. We collected precipitation and temperature data from the National Science and Technology Infrastructure Platform, solar radiation data from the China Meteorological Forcing Dataset, and vegetation cover remote-sensing data from the Moderate Resolution Imaging Spectroradiometer. We used the vegetation sensitivity index to identify areas sensitive to climate change and to determine which climatic factors were significant in this regard. The findings revealed a high degree of heterogeneity and non-linearity of ecosystem responses to climate change. Four types of heterogeneity were identified: longitude, altitude, ecosystem, and climate disturbance. Furthermore, the characteristics of nonlinear ecosystem responses to climate change included: (1) inconsistency in the controlling climatic factors for the same ecosystems in different geographical settings; (2) the interaction between different climatic factors results in varying weights that affect ecosystem stability and makes them difficult to determine; and (3) the hysteresis effect of vegetation increases the uncertainty of ecosystem responses to climate change. The findings are significant because they highlight the complexity of ecosystem responses to climate change. Furthermore, the identification of areas that are particularly sensitive to climate change and the influencing factors has important implications for predicting and managing the impacts of climate change on ecosystems, which can help protect the stability of ecosystems in the Qilian Mountains National Park.
分类: 医学、药学 >> 基础医学 提交时间: 2017-12-27 合作期刊: 《南方医科大学学报》
摘要: Objective To investigate the protective effects of tea polyphenols (TP) against myocardial ischemia/reperfusion (IR) injuries and explore the possible mechanisms. Methods Langendorff-perfused rat hearts were subjected to ischemia for 30 min followed by reperfusion for another 30 min. Myocardial function indices were measured by a left ventricular cannula via a pressure transducer connected to the polygraph in isolated Langendorff hearts and energy metabolism was measured using 31P nuclear magnetic resonance (NMR) spectroscopy. Whole-cell patch-clamp technique was used to record calcium inward current (ICa-L) in cultured rat cardiac myocytes. Results Compared with the control hearts, the ex vivo rat hearts with 2.5 mg/L TP treatment showed significantly increased left ventricular developed pressure (LVDP), maximal rise rate of LVDP (+ dp/dtmax), maximal fall rate of LVDP (-dp/dtmax), and coronary flow (CF) (P<0.05). During both cardiac ischemia and reperfusion phase, ATP and PCr levels were elevated significantly in TP-treated hearts compared with those in the control hearts (P<0.05). In cultured rat cardiac myocytes, ICa-L was remarkably decreased by TP at the doses of 2.5 and 5.0 mg/L (P<0.01). Conclusion Our results support a possible protective role of TP against myocardial IR injury by improving myocardial energy metabolism and inhibiting ICa-L in the cardiac myocytes.