Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-01-28 Cooperative journals: 《中国全科医学》
Abstract：
Objective To investigate the immediate effect of aerobic exercise on arterial stiffness in people with different blood glucose levels. Methods Those who participated in the sixth follow-up physical examination of the Kailuan Study from 2018 to 2020 and completed the brache-ankle Pulse Wave Velocity (baPWV) measurement before and after the secondary load test of the power vehicle were included in this study. According to fasting blood glucose levels, the observed subjects were grouped into quartile: Q1 (n=220) : FBG <5.00mmol/L,Q2 (n=240) : 5.00mmol/L≤ FBG <5.40mmol/L,Q3 (n=230) : 5.40mmol/L≤ FBG <5.81mmol/L,Q4 (n=234) : 5.81mmol/L≤ FBG .A generalized linear model was used to analyze the changes of baPWV before and after the secondary load test of power vehicle with different blood glucose levels. Results A total of 924 subjects met the inclusion criteria [age (36.93±7.72) years]. The baPWV measured immediately after 7 minutes of power vehicle secondary load test decreased by an average of 36cm/s from the resting level. After adjusting for confounding factors, baPWV decreased by 18.96[95%CI：-36.96,-0.96]（cm/s）more in the group with the lowest fasting glucose (Q1) than in the group with the highest fasting glucose (Q4). Conclusion Aerobic exercise can immediately improve the degree of arterial stiffness, but hyperglycemia attenuates the effect of aerobic exercise. This adverse effect was independent of traditional cardiovascular risk factors such as BMI and hypertension.
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