Risk Factors and Maternal and Neonatal Outcomes of Pregnant

分类： 医学、药学 >> 临床医学 提交时间： 2023-10-09 合作期刊: 《中国全科医学》

LU Yihan WANG Jiwen SUN Yue FENG Runrun HAN Yufei SONG Zhenzhen SUNYing DAI Huihua CHEN Xing

摘要： Background It is of great importance to standardize labor management for ensuring maternal and neonatal safety. Since the publication of the new stage of labor, the definition of prolonged labor has not been emphasized and it is recommended to minimize interventions during labor, therefore, the number of pregnant women with labor over 24 h is increased compared to the previous. Objective To analyze the risk factors and maternal and neonatal outcomes of pregnant women with labor over 24 h and discuss the labor management under the new stage of labor. Methods The clinical data of pregnant women received maternity examination and delivered at Department of Obstetrics, the First Affiliated Hospital with Nanjing Medical University from January to December 2022 were collected in the retrospective study. A total of 40 single birth pregnant women with normal fetal position and prolonged total labor（more than 24 h）were selected as the observational group, and 95 single birth pregnant women with normal fetal position and normal total labor（less than 24 h）were selected as the control group. Theage, BMI, gestational age of delivery, gestational diabetes, gestational hypertension, neonatal body mass, labor condition, analgesic delivery rate and delivery intervention rate of the two groups were compared. MultivariateLogistic regression analysis was used to explore the risk factors for total labor over 24 h. The maternal and neonatal outcomes including intrapartum fever, amniotic fluid contamination, mediolateral episiotomy, vaginal instrumental delivery, cervical laceration, postpartum hemorrhage, manual removal of placenta, fetal distress, neonatal asphyxia and referral to neonatal intensive care unit（NICU）were compared to screen the risk factors and analyse the maternal and neonatal outcomes of pregnant women with labor over 24 h. Results There were no significant differences in age, BMI, gestational age of delivery, gestational hypertension, gestational diabetes mellitus and neonate body mass between the two groups（P>0.05）. The first stage of labor, second stage of labor and total labor were longer and the rates of labor analgesia and labor intervention were higher in the observational group than the control group（P0.05）. There were no significant differences in the incidence of postpartum hemorrhage, vaginal instrumental delivery and fetal distress between the two groups（P>0.05）；the incidence of intrapartum fever, amniotic fluid contamination, mediolateral episiotomy, vaginal instrumental delivery, cervical laceration and referral to NICU in the observational group was higher than the control group（P<0.05）；no neonatal asphyxia occurred in both groups. Conclusion The rates of labor analgesia and labor intervention were significantly increased in pregnant women with total labor over 24 h due to prolonged labor. Although prolonged labor does not increase the incidence of postpartum hemorrhage, manual removal of placenta and neonatal asphyxia, it increases the incidence of intrapartum fever, amniotic fluid contamination, mediolateral episiotomy, vaginal instrumental delivery, cervical laceration and fetal distress. Obstetricians and gynecologists should pay attention to the adverse maternal and neonatal outcomes caused by prolonged labor and individualized management of labor.

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