摘要: Understanding the impact of meteorological and topographical factors on snow cover fraction (SCF) is crucial for water resource management in the Qilian Mountains (QLM), China. However, there is still a lack of adequate quantitative analysis of the impact of these factors. This study investigated the spatiotemporal characteristics and trends of SCF in the QLM based on the cloud-removed Moderate Resolution Imaging Spectroradiometer (MODIS) SCF dataset during 2000–2021 and conducted a quantitative analysis of the drivers using a histogram-based gradient boosting regression tree (HGBRT) model. The results indicated that the monthly distribution of SCF exhibited a bimodal pattern. The SCF showed a pattern of higher values in the western regions and lower values in the eastern regions. Overall, the SCF showed a decreasing trend during 2000–2021. The decrease in SCF occurred at higher elevations, while an increase was observed at lower elevations. At the annual scale, the SCF showed a downward trend in the western regions affected by westerly (52.84% of the QLM). However, the opposite trend was observed in the eastern regions affected by monsoon (45.73% of the QLM). The SCF displayed broadly similar spatial patterns in autumn and winter, with a significant decrease in the western regions and a slight increase in the central and eastern regions. The effect of spring SCF on spring surface runoff was more pronounced than that of winter SCF. Furthermore, compared with meteorological factors, a variation of 46.53% in spring surface runoff can be attributed to changes in spring SCF. At the annual scale, temperature and relative humidity were the most important drivers of SCF change. An increase in temperature exceeding 0.04°C/a was observed to result in a decline in SCF, with a maximum decrease of 0.22%/a. An increase in relative humidity of more than 0.02%/a stabilized the rise in SCF (about 0.06%/a). The impacts of slope and aspect were found to be minimal. At the seasonal scale, the primary factors impacting SCF change varied. In spring, precipitation and wind speed emerged as the primary drivers. In autumn, precipitation and temperature were identified as the primary drivers. In winter, relative humidity and precipitation were the most important drivers. In contrast to the other seasons, slope exerted the strongest influence on SCF change in summer. This study facilitates a detailed quantitative description of SCF change in the QLM, enhancing the effectiveness of watershed water resource management and ecological conservation efforts in this region.