Submitted Date
Subjects
Authors
Institution
  • A Study on the Prevalence Trend of Overweight and Obesity among Adults Aged 20 and above in Shanxi Province from 2010 To 2018

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-12-05 Cooperative journals: 《中国全科医学》

    Abstract: Background Overweight,obesity,and central obesity have become significant public health issues globally,affecting the well-being of residents. Analyzing the prevalence trends of overweight,obesity,and central obesity among residents in Shanxi Province can provide valuable scientific insights for the prevention and control of related diseases. Objective To analyze the prevalence and trends of overweight,obesity,and central obesity among adults aged 20 and above in Shanxi Province between 2010 and 2018. Methods The survey data of adults aged 20 and above in Shanxi Province were collected during four rounds of the China Chronic Disease Surveillance project from August 2010 to November 2018 (in 2010, 2013,2015,and 2018) to calculate the rates of overweight,obesity,and central obesity among adults aged 20 and above in different years,and analyze the prevalence trends of overweight,obesity and central obesity for different characteristics of the study subjects. Results From 2010 to 2018,the overall crude rates and age- and gender-standardized rates of overweight among adults aged 20 and above in Shanxi Province ranged from 37.7% to 40.1% and 36.1% to 39.6%,respectively,with no significant upward trend(Z=0.005,2.413;P=0.942,0.120). The overall standardized obesity rate,overall crude rate of central obesity and the standardized rate central of obesity increased from 17.2%,53.8%,and 52.4% in 2010 to 20.0%,61.6%,and 60.2% in 2018,respectively(Z=8.100,10.994,12.218;P<0.05). From 2010 to 2018,there was no significant upward or downward trends in the comparison of the overall crude overweight rate and the standardized overweight rate among adults aged 20 years and above by age,gender and region (P>0.05);the standardized overweight rate for males was higher than that for females(χ2 =4.259,P<0.05),while the standardized obesity rate was lower than that for females(χ2 =13.724,P<0.001) in 2013;no statistically significant differences between genders were observed at other time points (P>0.05);the overall obesity rate,male obesity rate,and both male and female central obesity rates in the age group of 20-39 years old showed an upward trend during the 8-year period (P<0.05). From 2010 to 2018,the standardized rates of overweight,obesity,and central obesity among urban residents were overall higher than those among rural residents(P<0.05). Specifically,significant differences were observed in the standardized overweight rates in 2013 and 2015,the standardized obesity rates in 2010 and 2015,and the standardized central obesity rates in 2015 and 2018(P<0.05). The results of the Joinpoint regression analysis revealed that,from 2010 to 2018,the age-standardized overweight rate among females in Shanxi Province exhibited a decreasing trend (APC=-0.57,P<0.05),while the age-standardized obesity rate among males showed an increasing trend(APC=2.72, P<0.05). The standardized rates of overweight,obesity,and central obesity among urban and rural residents remained relatively stable over the 8-year period(P>0.05). There was also no significant difference in the trends of these rates between different genders and regions (P>0.05). Conclusion From 2010 to 2018,the overweight rate among residents aged 20 and above in Shanxi Province remained stable,while the overall trends for obesity and central obesity rates showed an increasing trend. The prevention and control of obesity and central obesity should focus on the population aged 20-39 years to slow down the growth rate. For residents aged 40 and above ,as well as urban residents,targeted prevention strategies should be implemented,so as to control the prevalence of overweight,obesity,and central obesity.

  • Asset Assessment for Obesity Control among Middle School Students:a Qualitative Study

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-06-06 Cooperative journals: 《中国全科医学》

    Abstract: Background Adolescence is a high-risk period for obesity,and it is crucial and urgent to implement obesity control among adolescents. However,existing interventions commonly face challenges in sustainability and scalability. Asset assessment to identify and leverage existing community assets and strengths is essential to facilitate and maintain the implementation of these programs. Objective To assess assets for obesity control among middle school students,and to identify the advantages and deficiencies in the current policy,physical,social,and information environments,along with suggestions for improvements. Methods From 2023 to January 2024,purposive sampling method was adopted,face-to-face one-by-one interviews were conducted with 11 staff members involved in obesity control for middle school students from the Center for Disease Control and Prevention,Education Bureau,and three middle schools in a major city in East China. Additionally,eight parents and their children from each of the three schools were invited to participate in focus group discussions,with 6 groups and 8 participants per group. Thematic analysis was applied to analyze the interview data. Results This study found that the advantages in obesity control for middle school students primarily included policies and conditions ensured for obesity surveillance,nutritional school lunch and physical activity,along with media for health communication. The main deficiencies were the lack of specific policies for efficient obesity control,insufficient physical and social assets to support healthy eating and physical activity,and the quality and intensity of information assets supporting to facilitate changes in knowledge,attitude,and behaviors. In response to these challenges,participants suggested the implementation of both rigid regulations and flexible incentives,improvement of asset accessibility,encouragement of multi-stakeholder cooperation,and strengthening of health communication. Integrating existing assets and suggestions for improvement has formed an asset assessment checklist,corresponding to 10 assets from the policy environment,8 from the physical environment,20 from the social environment,and 12 from the information environment. Conclusion Several assets exist for obesity control among middle school students and identifies areas for improvement. Subsequent efforts in obesity control for middle school students should be made on promoting intervention strategies to better align with the context based on the asset assessment checklist to diagnose the current status of assets,thus enhancing the efficacy and sustainability of the program.

  • Research Progress of Sarcopenic Obesity in Cancer

    Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc. submitted time 2023-07-05 Cooperative journals: 《中国全科医学》

    Abstract: As the number of obese and elderly population increases worldwide,sarcopenic obesity is becoming associated with a higher risk of adverse events and outcomes in multiple clinical situations,including cancer. However,there is a lack of unified definition and diagnostic criteria for sarcopenic obesity,and the interaction between sarcopenic obesity and cancer needs to be further clarified. This paper systematically and comprehensively summarizes the relevant definitions and diagnostic methods of sarcopenic obesity,discusses its clinical impact on cancer patients in detail,including the impact on patients undergoing surgery and chemotherapy,and briefly describes the main prevention and treatment strategies. This paper reviews literature and concludes that the incidence of sarcopenic obesity is high in cancer patients,but its definition and diagnostic criteria are still controversial. Sarcopenic obesity is an independent predictor of cancer prognosis with important clinical application value.

  • 脂肪和相关基因与关系的研究进展

    Subjects: Biology >> Zoology submitted time 2017-10-11 Cooperative journals: 《动物营养学报》

    Abstract:脂肪和肥胖相关(FTO)基因是最近发现的一个与肥胖相关的基因。全基因组关联分析发现:FTO基因内有许多单核苷酸多态性位点(SNP),这些SNP位点与肥胖的发生密切相关。本文综述了FTO基因的发现、结构和组织表达特征,FTO基因SNP位点与肥胖之间关系,以及FTO基因通过调节摄食来影响肥胖的发生,以期为研究动物的肥胖机制提供一定的参考依据。

  • 与偏头痛发病相关性的meta分析

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-27 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To explore the relationship between obesity and migraine. Methods The online databases inlcuding PubMed, EMBASE, Wanfang, CNKI and Chinese Biological Medicine Database were searched for studies assessing the relationship between obesity and migraine according to the Cochrane Collaboration guidelines. Stata12.0 software was used for meta- analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the relationship between obesity and the risk of migraine. Result A total of 14 studies involving 193 274 individuals were included in the analysis. The results of meta-analysis showed that obese individuals had an increased risk of migraine by 19% as compared with normal weight individuals [OR, 1.19; 95%CI, 1.02-1.38; P=0.029) and by 19% as compared with non-obese individuals (OR, 1.19; 95%CI, 1.02-1.38; P=0.024). Conclusion Obesity is associated with an increased risk of migraine.

  • 影响呼吸系统抗感染的机制

    Subjects: Biology >> Zoology submitted time 2017-10-10 Cooperative journals: 《动物营养学报》

    Abstract:肥胖是由多因素引起的一种慢性代谢性疾病,也是一种系统性的低度炎症,同时影响着机体的能量代谢和免疫状态。大量研究报道,肥胖在一定程度上影响了呼吸系统的功能,增加了呼吸道感染的风险,同时调节了机体清除病原体的能力,使机体预后出现两极化。目前这种机制尚不清楚,明确的是脂肪组织的大量堆积,使炎性细胞浸润增加,炎性介质和脂肪因子的表达水平提高,这可能是肥胖改变肺脏对病原微生物敏感性的主要原因。本文就肥胖影响呼吸道抗感染的可能机制作一简要阐述,为深入探究肥胖与呼吸道感染之间的关系奠定一定的基础。

  • The Correlation of Dietary Inflammatory Index with Overweight,Obesity and Abdominal Obesity:a Meta-analysis

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-07-19 Cooperative journals: 《中国全科医学》

    Abstract: Background Dietary inflammatory index (DII),as a new index for quantitative evaluation of dietary inflammatory potential,has been widely used in various chronic disease studies,but the correlation between DII and different types of obesity has not been uniformly established. Objective To systematically evaluate the correlation of DII with overweight,obesity and abdominal obesity to provide reference for the prevention of different types of obesity. Methods CNKI,Wanfang,VIP,CBM,PubMed,Embase,Cochrane Library and Web of Science were searched by computer for cross-sectional studies of the association of DII with overweight,obesity and abdominal obesity from inception to January 10,2023. Risk of Bias Rating Scale of Agency for Healthcare Research and Quality (AHRQ) was used to evaluate the included studies. Meta-analysis was performed using RevMan 5.4.1 to calculate OR and 95% CI of the pooled data to assess the association of DII with overweight,obesity and abdominal obesity. Subgroup analyses were performed based on differences in gender,study geography,survey method,number of DII components,whether the sample population was healthy,diagnostic criteria,and type of DII grouping. Results A total of 20 studies from 9 countries with 214 808 subjects were included. Meta-analysis results showed that high levels of DII may be a possible risk factor for overweight 〔OR=1.12,95%CI(1.03,1.22),P=0.005〕,obesity 〔OR=1.56,95%CI(1.34,1.82),P<0.000 01〕,abdominal obesity 〔OR=1.42,95%CI(1.14,1.78),P=0.002〕. Subgroup analysis for differences in gender,study geography,survey method,number of DII components,whether the sample population was healthy,diagnostic criteria,and type of DII grouping in the original studies showed no significant between-group heterogeneity within each subgroup for the correlation between DII and overweight(P>0.05). Among the subgroups for the correlation between DII and obesity,the North American population 〔OR=1.57,95%CI(1.27,1.83)〕 had a higher proportion of obesity compared to populations from other geographic regions,and the results of the 24-h recall 〔OR=1.83,95%CI(1.39,2.42)〕 had a higher proportion of obesity compared to studies with other survey methods,and no significant heterogeneity was found among other groups. Among the subgroups for the correlation between DII and abdominal obesity,the North American population 〔OR=1.87,95%CI(1.44,2.44)〕 had a higher proportion of abdominal obesity compared to populations from other geographic regions,and no significant heterogeneity was found among other groups. The funnel plot distribution in this study had good symmetry,suggesting no significant publication bias. Conclusion DII diets may be a risk factor for overweight,obesity and abdominal obesity,and the association is more obvious in North American populations and in males. Increasing the intake of anti#2;inflammatory dietary components is important for the prevention and treatment of overweight,obesity and abdominal obesity.

  • Title Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement:Interpretation

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2022-09-05 Cooperative journals: 《中国全科医学》

    Abstract: In recent years,The international expert pool of ESPEN and EASO experts appointed by the United Nations has conducted a systematic evaluation of sarcopenic obesity.ESPEN and EASO issued in February,about the definition diagnostic criteria of sarcopenic obesity guide interpretation ,is implied on muscle fat has carried on the detailed elaboration ,and the definition of sarcopenic diagnose reach a consensus,provides reference for the researchers and clinical workers ,in order to reduce provide standards suitable for clinical practice.The author mainly interprets the content of the guidelines to provide reference for the diagnosis of sarcopenic obesity in China.

  • 芦丁对 芦丁对诱发的雄性小鼠生殖损伤的保护作用

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2018-01-25 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To study the effect of rutin on body weight and obesity-induced reproductive impairment in male mice. Methods Twenty-four male mice were randomized equally into normal control group, high-fat diet group (HFD group), and HFD+rutininterventiongroup(HRUgroup).After28daysoftreatments,thetestesandepididymisofthemicewerecollected for detection of total cholesterol (TC) and triglycerides (TG) levels and for pathological examinations with HE staining. The expressions of related genes was detected with real-time PCR, and Western blotting was used to detect the expression of Ucp1 protein in the samples. Results After 28 days of treatments, the mean body weight was lower in mice with rutin intervention than in those in HFD group. The mice in HFD group showed significantly higher TG levels in the testis and epididymis and higher TC levels in the epididymis than those in the control and HRU groups. In HFD group, the testis and the epididymis displayed loosened structures with abnormalcell structure, and the number ofmature spermatozoa in the lumen was decreased and the mobility of the sperms was reduced; all these changes were significantly alleviated in HRU group. The expression levels of Ucp1 mRNA and protein increased (P<0.05) and the expressions of Mcp1 and TNF-α decreased significantly in the mice after rutin treatment (P<0.05). Conclusion Rutin can effectively inhibit rapid increase of body weight and protect against obesity-inducedreproductiveimpairmentinobesemice.

  • Comparison of urine proteome between obese people and normal people

    Subjects: Biology >> Biochemistry Subjects: Biology >> Molecular Biology submitted time 2024-01-02

    Abstract: Objective: Comparison of urine proteome between obese people and normal people.
    Methods: Urine samples from obese and normal people were collected and identified by non-label quantitative proteomics using high performance liquid chromatography tandem mass spectrometry (LC-MS/MS). The difference proteins of urine proteome between obese and normal people were screened for protein function and biological pathway analysis. The urine proteome of obese individuals was compared with that of normal people, and the common differential proteins were counted to analyze the protein function and biological pathways. Reported biomarkers of obesity were searched in the urine proteome of obese individuals.
    Results: 38 different proteins can be identified in the urine proteome of obese people compared with normal people, some of which have been reported to be related to metabolism and obesity, and the biological processes of differential proteins are also related to metabolism and other processes. 8 common differential proteins in the urine proteome of obese individuals and normal people, among which some proteins have been reported to be related to metabolism and obesity, and the biological processes of differential proteins are also related to metabolism and other processes. Among the differential proteins in the urine proteome of obese individuals compared with the normal people, the reported obesity biomarkers can be matched.
    Conclusions: The urine proteome can distinguish the obese people, and the differential proteins in the urine proteome have key proteins that are known to be related to obesity and metabolism, and the biological processes of differential proteins also related biological processes such as nutrition and metabolism. Urine proteome has the potential to explore the pathogenesis of obesity and provide personalized treatment.

  • 腹型的中医外治法研究进展

    Subjects: Nursing >> Nursing submitted time 2022-09-06

    Abstract:本文介绍了腹型肥胖的相关概念,梳理了腹型肥胖中医外治技术以及中医外治技术的联合应用并进行综述。从中医视角看,对腹型肥胖施以刮痧、耳穴贴压、针灸、穴位埋线等中医外治法,有助于预防和治疗腹型肥胖,减缓因腹型肥胖引起的脂代谢紊乱体能下降,内分泌失调等问题。

  • 抵抗素诱导机体胰岛素抵抗的炎症机制

    Subjects: Biology >> Zoology submitted time 2017-10-23 Cooperative journals: 《动物营养学报》

    Abstract:抵抗素是一种脂肪因子,被证明与胰岛素抵抗密切相关,但其作用机制尚不明确。近年研究表明抵抗素参与了肥胖有关的炎症进程,对胰岛素敏感组织(脂肪、肝脏)炎症状态起到重要调控作用。肥胖诱导的慢性低度炎症是导致机体胰岛素抵抗的重要因素,抵抗素通过对炎症的调控参与肥胖机体胰岛素抵抗的发生。本文主要从组织及分子层面探讨抵抗素诱导胰岛素抵抗的炎症机制,为进一步了解抵抗素在肥胖相关疾病病理机制中的作用提供一些思路。

  • Intestinal Flora:an Important Participant in Childhood Obesity

    Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-02-19 Cooperative journals: 《中国全科医学》

    Abstract: The increasing incidence of childhood obesity has emerged as a novel challenge in the realm of global public health. Studies have demonstrated that alterations in the composition of intestinal flora during the early stages of life contribute to the development of obesity by influencing nutrient absorption and metabolism,triggering inflammatory responses,and regulating the communication between the gut and brain. Currently,Bifidobacterium and Akkermansia muciniphila have been found to reduce body fat content,exhibit anti-inflammatory properties,and enhance intestinal barrier function,whereas Prevotella is strongly associated with improvements in individual glucose metabolism induced by dietary fiber. Translational application of specific intestinal flora benefits to body glycolipid metabolism is helpful for the early prevention and therapy of pediatric obesity. This review elucidates the impact of early-life changes in intestinal flora composition on childhood obesity explores the mechanisms by which intestinal flora contributes to obesity pathogenesis,and specifically focuses on recent advances in utilizing short-chain fatty acids for the regulation of intestinal flora and the amelioration of obesity,aiming to provide a theoretical foundation for the intervention of childhood obesity from the perspective of intestinal flora.

  • 体重污名:对的歧视与偏见 *

    Subjects: Psychology >> Developmental Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》

    Abstract: Weight stigma refers to the social stigma to overweight or obese individuals, including discrimination, prejudice and stereotype, which is mainly evaluated by the public and the stigmatized groups themselves. Weight stigma exerts negative and interconnected impacts on individuals’ body, mind and behavior. Currently, there are three main dimensions of weight stigma interventions (i.e., reducing public stigma and conducting physical and psychological intervention on overweight and obese individuals). More theoretical and practical researches in future should be done to reveal the mechanism of effects of weight stigma and develop effective measurements and intervention strategies

  • 移动医疗APP中关于和Ⅱ型糖尿病及代谢减重手术患教信息质量的调查

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《分子影像学杂志》

    Abstract: Objective To investigate the quality of teaching information obesity and bariatric surgery on mobile medical Appsin China. Summarizes the quality of teaching information on mobile medical Apps whether meet the needs of patients.Methods We searched the key words “Yi” on the platform of “Apple store”, “Yingyongbao” and downloaded 63 relatedApps. After screening, a total of 28 Apps’ related teaching information were evaluated using “Silberg scale” and “Abott scale”.Comparing with the same scores of the foreign medical Apps, evaluate the quality of teaching information obesity and bariatricsurgery on mobile medical Apps in China. Results A total of 28 Apps’ teaching information were evaluated, the mean score of“Silberg scale” was 2.96±.96l. The mean score of “Abott scale” was 1.61±0.61. The score for the “Quality of content” was3.85±1.76. The quality of teaching information obesity and bariatric surgery is poor. It was lacked of sufficient accuracy andauthority. The content was not that specific. More, the information was lacked of timely updating and modification.Conclusion The mobile medical Apps in China are supposed to improve the veracity and authority of teaching information.Especially in terms of author authentication, information source, information renew and modification of teaching information.

  • Changes of serum Irisin level in obese or overweight patients with type 2 diabetes mellitus

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-07-20 Cooperative journals: 《中国全科医学》

    Abstract: Background Obesity can lead to insulin resistance (IR) and lead to type 2 diabetes mellitus (T2DM), which seriously affects human health. Irisin is a newly discovered muscle and adipocytokine, which plays an important role in metabolic regulation. It is worth studying how its level changes in T2DM patients with obesity or overweight.  Objective To investigate the level of serum Irisin in  obesity or overweight patients with type 2 diabetes mellitus (T2DM), and to explore its correlation with body mass index (BMI), blood glucose, blood lipids, homeostasis insulin resistance index (HOMA-IR) and other factors.Methods A total of 119 T2DM patients hospitalized in the Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University from December 2019 to June 2021 were selected. According to BMI, they were divided into diabetic overweight group (n=78) and diabetic normal weight group (n=41).Healthy subjects in our hospital during the same period were selected as the control group (n=52).Blood pressure, BMI, blood lipid, Glycosylated hemoglobin A1c(HbA1c), fasting blood glucose (FBG), fasting insulin (FINS), HOMA-IR and Irisin levels were recorded.Results There were statistically significant differences in blood pressure, BMI, triglyceride (TG), high density lipoprotein cholesterol (HDL-C), HbA1c, FBG, FINS and HOMA-IR among three groups (P<0.05).The level of Irisin in normal weight diabetic group was lower than that in control group, and the level of Irisin in obesity or overweight diabetic group was lower than that in control group and normal weight diabetic group (P<0.05). Spearman correlation analysis showed that serum Irisin level was positively correlated with HDL-C, and negatively correlated with systolic blood pressure, diastolic blood pressure, BMI, TG, HbA1c, FBG, FINS, HOMA-IR.Multiple linear regression analysis showed that DBP, HbA1c, FBG and FINS were the influential factors of serum Irisin level (P<0.05).Conclusion  The level of serum Irisin in T2DM patients with obesity or overweight is decreased, which is related to BMI, blood pressure, blood lipid and IR.

  • 过度喂养建立斑马鱼幼鱼模型

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-27 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To establish a diet-induced obesity model in zebrafish larvae. Methods At 7 days post-fertilization (dpf),200 zebrafish larvae with normal development were randomly allocated to two groups with the feeding quantity of 30 mg per day (normal feeding group) or 180 mg per day (overfed group) for 20 days. The weight, length, BMI, triglyceride (TG) and total cholesterol (TCH) of each group were measured. Whole-mount Oil Red O staining, frozen Oil Red O staining and hematoxylin-eosin (HE) staining were used to estimate the rate of hepatic steatosis and liver histology of the zebrafish. The dynamic change of hepatic lipid droplets and distribution of adipose tissue were observed with Nile Red staining in overfed zebrafish in vivo. Results The weight, length, BMI and TG of overfed zebrafish were significantly increased compared with those in normal feeding group. Whole-mount Oil Red O staining showed that the percent of hepatic steatosis in overfed group (89.4%) was markedly higher than that in normal feeding group (20.7%). Macrovesicular steatosis was observed in the liver of the overfed larvae. Nile Red staining visualized hepatic lipid droplets and the distribution of larval adipose tissue, which increased with feeding time in the overfed zebrafish. Starving larvae showed depletion of fat and hepatic lipid, and adipose tissue was induced after refeeding. Conclusions We successfully established an diet-induced obesity model in zebrafish larva, in which Nile Red staining allows in vivo observation of the adipocytes and hepatic lipid droplets.

  • 白藜芦醇的生物学功能及其在畜禽生产中的应用

    Subjects: Biology >> Zoology submitted time 2017-11-08 Cooperative journals: 《动物营养学报》

    Abstract:白藜芦醇是一种天然多酚类化合物,存在于多种植物中。近年来,白藜芦醇因具有多种有益生物学功能,得到了人们的广泛关注,将其作为一种新型的饲料添加剂应用于畜禽生产已见报道。本文综述了白藜芦醇的抗氧化、抗炎症、抗肥胖功能及其在畜禽生产中的应用现状,旨在为白藜芦醇在畜禽生产中的合理应用提供依据。

  • Meta-analysis of the Effects of Aerobic Exercise on Executive Function in Overweight and Obese

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-02-05 Cooperative journals: 《中国全科医学》

    Abstract: Background Studies have confirmed that executive function in overweight and obese children is closely related to obesity and may have a bidirectional association. Aerobic exercise,as an effective intervention,can effectively promote their brain development and cognitive function,especially executive function,but the quantitative relationship of the improvement effect still needs to be further explored. Objective To systematically evaluate the intervention effect of aerobic exercise on executive function-related indexes in overweight and obese children. Methods Randomized controlled trials of aerobic exercise interventions for executive function in overweight and obese children were searched in CNKI,Wanfang Data,CBM,Cochrane Library,PubMed,Embase,and Web of Science databases,and the timeframe for searching was from the establishment of each database to July 2023. The quality of the included literature was assessed according to the Cochrane Risk of Bias Assessment Tool,and Meta-analysis of outcome indicators was performed using RevMan 5.3 and Stata 16.0 software. Results Nine randomized controlled trials,including 940 overweight and obese children,were finally included. The results of Metaanalysis showed that a single session of aerobic exercise intervention was effective in improving the executive function of overweight and obese children(WMD=-6.98,95%CI=-11.89 to -2.07,P=0.005). Subgroup analyses showed no significant differences in the improvement of any of the executive function subcomponents in overweight and obese children with a single intervention duration of less than 30 minutes of aerobic exercise(WMD=-0.84,95%CI=-9.37 to 7.68,P=0.85);aerobic exercise with a single intervention duration longer than 30 minutes improved inhibitory function in overweight and obese children(WMD=-10.50,95%CI=-19.15 to -1.85,P=0.02). When a long-term exercise intervention was carried out(the intervention period was 8 weeks),in contrast to the control group,the aerobic exercise improved interference control in overweight and obese children(WMD=-0.16,95%CI=-0.18 to -0.14,P<0.000 01),on planning(WMD=4.20,95%CI=-8.34 to 16.73,P=0.51),attention(WMD=0.41,95%CI=-12.08 to 12.91,P=0.95),synchronization(WMD=3.93,95%CI=-8.22 to 16.08,P=0.53),and continuity(WMD=2.48,95%CI=-9.18 to 14.14,P=0.68)were not significantly improved. Conclusion Aerobic exercise for a single long period of time had a selective positive effect on executive function subcomponents in overweight and obese children,and aerobic exercise for a long period of time with a fixed frequency and duration improved interference control in overweight and obese children,but did not produce an improvement in planning,attention,synchronization,or continuity.
     

  • The Characteristic and Predictive Factors of Food Preference Changes in Patients Undergoing Bariatric Surgery

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-11-14 Cooperative journals: 《中国全科医学》

    Abstract: Background The change of food preference after bariatirc surgery is an important reason for weight loss. It is important to assess the specific characteristics of food preference change and analyze its predictive factors. However, the existing research results are quite different. Objective To investigate the characteristics of food preference change and weight loss outcome of patients undergoing bariatirc surgery, also analyze the predictive factors of food preference change. Methods A convenient sampling method was used to select 245 patients undergoing bariatric surgery who were admitted to the follow-up outpatient department of the First Affiliated Hospital of Nanjing Medical University from February 2022 to August. The general information and the food preference change data of patients was collected. Independent sample t-test was used to compare whether the change of food preference after bariatric surgery affected the weight loss outcome. Univariate analysis and disordered multi-classification Logistic regression were performed to analyze the predictive factors. Results 237 valid questionnaires were collected, and the incidence of food preference changes after bariatric surgery was 97%. Independent sample t-test showed that the change of food preference after bariatric surgery affected the value of TWL%, weight and BMI loss significantly (P<0.05). Logistic regression analysis showed that preoperative comorbidities and postoperative time were the predictors of changes in preferences for vegetables and fruits (P<0.05); preoperative comorbidities was the predictor of changes in preference for high-quality protein foods (P<0.05); residence was the predictor of changes in preference for spicy foods (P<0.05); gender was the predictor of changes in preferences for snacks, high-fat meat, and sweet drinks (P<0.05); the operation method was the predictor of the preference change for carbon water food (P<0.05); gender and postoperative time were the predictors of changes in preferences for sweet food (P<0.05). Conclusions The incidence of food preference changes in patients undergoing bariatric surgery is high, showing a decrease in their preference for high calorie foods and an increase in their preference for healthy foods. Different surgical methods, gender, postoperative time, residence and the preoperative comorbidities are predictors of the food preference changes after bariatric surgery. The medical staff should identify the target population at early stage, pay more attention to the postoperative dietary education, in order to improve the postoperative dietary experience and effectively ensure the effect of weight loss surgery.