Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-05-31 Cooperative journals: 《中国全科医学》
Abstract： To provide researchers with a comprehensive understanding of the Psychology and Behavior Investigation of Chinese Residents（PBICR），this paper introduces its background and features from four aspects. In terms of design concepts，PBICR focuses on many aspects of mental health and health behaviours in the Chinese population，takes full account of timeliness and efficiency，adheres to the original intention of data openness and data sharing，builds a high-quality database with a large-sample，multi-centre，repetitive，nationwide cross-sectional design，and promotes data mining and exchange and cooperation; in terms of survey implementation，PBICR adopts a proportional to the size of the population，a combination of multilayer sampling and quota sampling，obtains data through face-to-face field surveys，and implements a rigorous sampling methodology. In terms of survey implementation，PBICR adopts a combination of population size-proportional，multistage random sampling and quota sampling sampling，and obtains data through face-to-face field surveys with strict quality control to ensure the representativeness and reliability of the samples; in terms of output，PBICR's research content is rich and updated in line with international hotspots，which can satisfy the demand for research on diversified variables and data，and the results of its past research have a higher influence in many fields such as public health，management，communication，and psychology; Looking ahead，PBICR will gradually complete the construction of databases from the general database to sub-databases，pay attention to special populations and a wide range of regions around the world，add tracking surveys and biomedical data research perspectives，and have great research potential to drive research on the mental and behavioural health of Chinese residents through the overall layout of the multi-dimensional.
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-30
Abstract： Cone-beam computed tomography (CBCT) is mostly used for position verification during the treatment pro#2;
cess. However, severe image artifacts in CBCT hinder its direct use in dose calculation and adaptive radiation
therapy re-planning for proton therapy. In this study, an improved U-Net neural network named CBAM-U-Net
was proposed for CBCT noise reduction in proton therapy, which is a CBCT denoised U-Net network with con#2;
volutional block attention modules. The datasets contained 20 groups of head and neck images. The CT images
were registered to CBCT images as ground truth. The original CBCT denoised U-Net network, sCTU-Net, was
trained for model performance comparison. The synthetic CT(SCT) images generated by CBAM-U-Net and the
original sCTU-Net are called CBAM-SCT and U-Net-SCT images, respectively. The HU accuracies of the CT,
CBCT, and SCT images were compared using four metrics: mean absolute error (MAE), root mean square error
(RMSE), peak signal-to-noise ratio (PSNR), and structure similarity index measure (SSIM). The mean values of
the MAE, RMSE, PSNR, and SSIM of CBAM-SCT images were 23.80 HU, 64.63 HU, 52.27 dB, and 0.9919,
respectively, which were superior to those of the U-Net-SCT images. To evaluate dosimetric accuracy, the range
accuracy was compared for a single-energy proton beam. The γ-index pass rates of a 4 cm × 4 cm scanned
field and simple plan were calculated to compare the effects of the noise reduction capabilities of the original
U-Net and CBAM-U-Net on the dose calculation results. CBAM-U-Net reduced noise more effectively than
sCTU-Net, particularly in high-density tissues. We proposed a CBAM-U-Net model for CBCT noise reduction
in proton therapy. Owing to the excellent noise reduction capabilities of CBAM-U-Net, the proposed model
provided relatively explicit information regarding patient tissues. Moreover, it can be used in dose calculation
and adaptive treatment planning in the future.
YES
Subjects: Nursing >> Nursing submitted time 2024-05-30
Abstract： This paper reports a case of a child with spinal cord injury caused by epidural hematoma who underwent successful treatment with a combination of Western and Chinese medicine, and summarizes the importance of nursing care in the patient’s treatment process. The case was treated with Western medical methods such as airway care, antibiotic therapy, and nutritional nerve support, and combined with Chinese medicine treatments such as acupuncture, massage, finger point therapy, and pulmonary rehabilitation. The patient was able to walk intermittently and independently after one month of hospitalization, and all body functions gradually returned to normal. This case suggests that early Chinese medicine intervention and nursing care can have a positive impact on the treatment and recovery of the disease.
Peer Review Status:
Awaiting Review
Subjects: Nuclear Science and Technology >> Nuclear Science and Technology submitted time 2024-05-30
Abstract： [Background]: The single-phase reversed flow in inverted U-tubes of steam generator (SG) leads to increasing flow resistance and decreasing heat transfer area, so it is meaningful to study this phenomenon. [Purpose]: The water level of the secondary side in SG can influence the single-phase reversed flow, it is necessary to clarify its influence mechanism from a more general viewpoint. [Methods]: The dimensionless conservation equations were derived first, and the extreme point was obtained based on the equations. Then the effect of the water level of the secondary side under conditions of different lengths, dimensionless resistance number, and dimensionless heat transfer number was analyzed. [Results]: The decrease in the water level leads to the critical point of the single-phase reversed flow gradually approaching the origin, the influence law of the water level is the same under different pipe length conditions. As the water level decreases, the influence of the dimensionless resistance number and dimensionless heat transfer number on the critical point gradually reduces. [Conclusions]: This study theoretically proves that the effect of secondary water level on single-phase reversed flow is not conducive to the occurrence of backflow, and explains the reasons from a mechanistic perspective, which can assist in accident analysis of related nuclear power plants.
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-30
Abstract： Relativistic isobar ($^{96}_{44}$Ru+$^{96}_{44}$Ru and $^{96}_{40}$Zr+$^{96}_{40}$Zr) collisions have revealed intricate differences in their nuclear size and shape, inspiring unconventional studies of nuclear structure using relativistic heavy ion collisions. In this study, we investigate the relative differences in the mean multiplicity ($R_{ langle N_{ rm ch} rangle}$) and the second- ($R_{ epsilon_{2}}$) and third-order eccentricity ($R_{ epsilon_{3}}$) between isobar collisions using Optical and Monte Carlo Glauber models. It is found that initial fluctuations and nuclear deformations have negligible effects on $R_{ langle N_{ rm ch} rangle}$ in most central collisions, while both are important for the $R_{ epsilon_{2}}$ and $R_{ epsilon_{3}}$, the degree of which is sensitive to the underlying nucleonic or sub-nucleonic degree of freedom. These features, compared to real data, may probe the particle production mechanism and the physics underlying nuclear structure.
YES
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-30
Abstract： DD4hep serves as a generic detector de Conversely, Filmbox~(FBX) stands out as a widely used 3D modeling file format within the 3D software industry. In this paper, we introduce a novel method that can automatically convert complex HEP detector geometries from DD4hep de The feasibility of this method was demonstrated by its application to the DD4hep de The automatic DD4hep--FBX detector conversion interface provides convenience for further development of applications, such as detector design, simulation, visualization, data monitoring, and outreach, in HEP experiments.
YES
Subjects: Psychology >> Developmental Psychology submitted time 2024-05-29
Abstract： Prosocial behavior is a major aspect of social functioning in childhood and adolescence. Research has indicated relations between parental warmth and children’s prosocial behavior. However, the meachanims for the relations remain unclear, especially in non-Western countries. The primary purpose of the present longitudinal study was to explore the role of children’s group orientation in linking parental warmth and children’s prosocial behavior. Group orientation, characterized as concern for group welfare and interpersonal harmony, has been particularly emphasized in socialization and believed to regulate children’s behaviors in social interaction in Chinese collectivistic society. To address the gap in the literature, this study examined the transactional relations among perceived parental warmth, child group orientation, and child prosocial behavior with a focus on the mediating effects of group orientation.
Multi-wave longitudinal data were collected each year from Grade 4 to Grade 6 in a sample of five randomly selected regular public elementary schools in China (initial N = 1033; 49.5% girls; initial Mage = 10.28 years, SD = 0.69). Data on parental warmth, group orientation, and prosocial behavior were obtained from multiple sources including self-reports and teacher ratings. Measurement invariance tests were first conducted for the measures with multiple indicators across three times of measurement. Next, latent cross-lagged panel models were constructed to examine the relations among maternal/paternal warmth, group orientation, and prosocial behavior controlling children’s gender and parental educational level. Multigroup analyses were also conducted to examine gender differences in the models.
The results showed that maternal warmth positively predicted later prosocial behavior, and child prosocial behavior positively predicted later paternal warmth. Both paternal and maternal warmth positively predicted child group orientation, which in turn positively predicted child prosocial behavior; group orientation was a mediator of the contributions of parental warmth to prosocial behavior. Multigroup analyses showed no significant gender differences in the cross-lagged paths.
The findings highlight the crucial role that group orientation plays in the link between parental warmth and children’s prosocial behavior. The study has significant implications for early intervention to promote children’s prosocial behavior.
Subjects: Psychology >> Cognitive Psychology submitted time 2024-05-29
Abstract： Writing is a complex perceptual-motor process that involves both central cognitive coding and peripheral motor execution. It requires a lot of cognitive resources and is therefore susceptible to physiological aging. Research based on written products has found that older adults always show variations in font size, stroke inversions, reduced smoothness, and increased error rates. Studies on the writing process have revealed that older adults tend to show slower responses, increased pauses, prolonged execution, decreased speed, and uneven pen pressure. Cognitive aging in writing primarily stems from neurodegeneration of the brain, decline of sensory-motor mechanisms, and interference from hormonal changes or bone loss to hand movements. Future research should focus on the synchrony and asynchrony of aging in different writing processes, as well as the universality and specificity of cognitive aging in writing. Meanwhile, research should also be conducted to develop and apply clinical diagnostic criteria for cognitive aging in writing.
Subjects: Physics >> Nuclear Physics submitted time 2024-05-29
Abstract： The fast X-ray imaging beamline (BL16U2) at Shanghai Synchrotron Radiation Facility (SSRF) is a new beamline that provides X-ray micro-imaging capabilities across a wide range of time scales, spanning from 100 ps to μs and ms. This beamline has been specifically designed to facilitate the investigation of a wide range of rapid phenomena, such as the deformation and failure of materials subjected to intense dynamic loads. In addition, it enables the study of high-pressure and high-speed fuel spray processes in automotive engines. The light source of this beamline is a cryogenic permanent magnet undulator (CPMU) that is cooled by liquid nitrogen. This CPMU can generate X-ray photons within an energy range of 8.7-30 keV. The beamline offers two modes of operation: monochromatic beam mode with a liquid nitrogen-cooled double-crystal monochromator (DCM) and pink beam mode with the first crystal of the DCM out of the beam path. Four X-ray imaging methods were implemented in BL16U2: single-pulse ultrafast X-ray imaging, microsecond-resolved X-ray dynamic imaging, millisecond-resolved X-ray dynamic micro-CT, and high-resolution quantitative micro-CT. Furthermore, BL16U2 is equipped with various in situ impact loading systems, such as a split Hopkinson bar system, light gas gun, and fuel spray chamber. Following the completion of the final commissioning in 2021 and subsequent trial operations in 2022, the beamline has been officially available to users from 2023.
YES
Subjects: Physics >> Nuclear Physics Subjects: Physics >> Geophysics, Astronomy, and Astrophysics submitted time 2024-05-29
Abstract： It is hypothesized that, though atomic nuclei are made of nucleons, strongly interacting matter with baryon number from $A simeq 10^{3-9}$ to $ sim 10^{57}$ would be composed of strangeons if Nature favors always the flavor symmetry of quarks. According to that logic, strangeon matter with $A sim 10^{57}$ could manifest in the form of pulsar-like compact stars, and multi-messenger observations with advanced facilities (e.g., China’s FAST) could eventually provide a disproof/proof. It is worth emphasizing that this point of view, based on established “old physics”, may have particular consequences for understanding our material world, for both normal luminous matter and the dark sector.
Peer Review Status:Awaiting Review
Subjects: Psychology >> Other Disciplines of Psychology submitted time 2024-05-29
Abstract： Aggressive behavior refers to the psychological and behavioral tendency of an individual to intentionally hurt others in a direct or indirect way, so that the body and mind of the target of attack are adversely affected. The problem behavior of middle school students in the adolescent period is increasing, and the severity and danger of aggressive behavior are gradually increasing. Many studies have reported the effect of social anxie ty on aggressive behavior, but the internal mechanism of the how has not been fully explored. Therefore, this study explores the influence of emotion and cognition on behavior from the perspective of cognitive behavior theory. Specifically, this study examined whether social anxiety has an indirect effect on aggression through verbal fluency and whether this effect is moderated by emotional intelligence./t/nA total of 905 middle school students (mean age = 15.4 years, SD =1.8) participated in the study, who anonymously filled out questionnaires on social anxiety, verbal fluency, emotional intelligence, and aggressive behavior. All measures have good reliability and validity./t/nAfter controlling for sex, age, place of origin and whether the child is the only child, the structural equation model shows that: (1) Social anxiety can significantly predict aggressive behavior of middle school students under the condition of controlling gender, age and whether they are only children; (2) Social anxiety can predict aggression of middle school students through the mediating effect of verbal fluency; (3) The mediating effect of verbal fluency is regulated by emotional intelligence.pecifically, compared with high emotional intelligence middle school students, social anxiety of low emotional intelligence middle school students has greater predictive effect on verbal fluency and aggression./t/nThese findings help to reveal the mechanism of social anxiety on aggressive behavior of middle school students. On the one hand, verbal fluency plays a mediating role in the influence of social anxiety on aggression of middle school students. Therefore, we should pay attention to the influence of verbal fluency, which is easy to be neglected but plays an important role in communication, on aggression of middle school students. On the other hand, students with low emotional intelligence were more prone to aggressive behavior due to social anxiety and poor verbal fluency. Therefore, the intervention and prevention of aggressive behavior can start from the perspective of cultivating middle school students’ emotional intelligence and improving their verbal communication ability.
Peer Review Status:Awaiting Review
Subjects: Digital Publishing >> Internet Journals Subjects: Library Science，Information Science >> Information Science submitted time 2024-05-28
Abstract： Purposes The four updates of Principles of Transparency and Best Practice in Scholarly Publishing from 2013 to 2022 are nurtured in the context of global open science publishing, and may shed insight on the development for academic journals in China. Methods The first to the fourth versions of the principles were obtained through the website of Open Access Scholarly Publishing Association (OASPA). Taking individual principle as a unit of analysis, a longitudinal comparison of the principle details were compared to systematically reveal their differences and development over time. Focusing on the principles of the lasted version which were analyzed in the article, suggestions for the development of academic journals in China were summarized. Findings From 2013 to 2022, four versions of the principles were published, aiming to ensure the quality and credibility of academic research by improving the transparency of academic publishing. Compared with previous versions, the fourth version provided more detailed instructions on how to achieve transparency and best practices focusing on 16 principles pertaining to four dimensions: journal content, journal practices, organization, and business practices, with considerations of the practices achievable by journals in different disciplines, regions, and scales, to cope with the challenges by open science. Conclusions The principles would be helpful for the improvement of China’s academic publishing transparency and ensure the quality and credibility of China’s academic research. Chinese academic journals should increase awareness and participation in open science movement, work on network security maintenance and website information transparency, clearly describe copyright and licensing information in journal policies to protect intellectual property rights, and safeguard editorial independence to ensure academic value.
Subjects: Psychology >> Management Psychology submitted time 2024-05-28
Abstract： Leadership development has emerged as a cutting-edge research topic in organizational management and a practical challenge in human resource management. Previous studies have focused on offering courses and challenging work experiences inside enterprises to cultivate leadership, but these approaches face limitations in enhancing effectiveness. Recent research has focused on leadership development across multiple domains with the “whole person” approach, especially the effects of non-work experience on leadership development in the working domain. We adopt the family-work enrichment perspective to explore how parental experience influences leader effectiveness, examining the process through instrumental, affective, and efficiency enrichment paths. We propose a conceptual model for leadership development by adopting the perspective of “parent-leader enrichment”. Future research should clarify the qualitative and quantitative relationship between parental experience and leader effectiveness, and explore interventions aimed at boosting enrichment awareness, identity, and efficacy to enhance leadership development in practice.
Subjects: Nursing >> Nursing submitted time 2024-05-28
Abstract：1例老年女性压力性尿失禁患者的护理经验。住院期间进行中西医联合疗法治疗，护理要点包括：康复训练护理，耳穴压豆治疗，用药护理，心理护理等。经过治疗和护理，患者压力性尿失禁情况明显好转。
Peer Review Status:Awaiting Review
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-28
Abstract： Ion beam radiotherapy is increasingly being used for tumor treatment. Currently, the use of traditional X-ray computed tomography (CT) for treatment planning of ion-beam radiotherapy has significant relative stopping power (RSP) errors. A more ideal approach is to directly use ion beams to generate patient images for treatment planning so as to avoid RSP conversion and reduce RSP errors. In this study, the Monte Carlo program Geent4/Gate was adopted to establish an ion-CT simulation platform, designed two sets of ion CT systems, ideal and real, and reconstructed images using the maximum likelihood method and ASD-POCS algorithm. The effects of the ideal and real settings, multiple energies, and different ion types on the RSP error of phantom reconstruction were investigated. The results show that the relative error of RSP for 330MeV protons in both the ideal and real settings was less than 1.547%, and the RSP reconstruction error in the ideal settings was much smaller than that in the real settings. The RSP reconstruction error of each material under realistic settings is close to three times that under ideal settings. The relative errors of RSP for protons decrease with the increase of incident energy. The relative errors of RSP were the biggest at 230MeV, and were2.855%、2.468%、1.653%、and 2.553% in sulfur, phosphorus, carbon, and calcium materials. The RSP relative error reached its minimum at 330MeV, with 0.181%, 0.351%, 0.250%, and 0.245% in sulfur, phosphorus, carbon, and calcium materials. At energy of 330MeV/u for carbon ions , the RSP relative errors in sulfur, phosphorus, carbon, and calcium materials were 0.060%, 0.281%, 0.150%, and 0.082%, respectively, all within 0.281%. And the RSP relative errors were much smaller than those of protons under the same conditions. Thus, compared with proton CT, carbon ion-beam CT seems more possible to provide accurate RSP data for treatment planning for ion-beam radiotherapy..
Subjects: Nuclear Science and Technology >> Nuclear Science and Technology submitted time 2024-05-28
Abstract： The search and localization of unknown radioactive sources is an important research topic in the field of nuclear security inspection and nuclear emergency response. In order to improve the source finding efficiency and adapt to the multi-source environment detection, a particle filtering source finding method integrating the angle of arrival is proposed. Firstly, a hardware platform combining autonomous localization and angle-of-arrival sensing is constructed to introduce position and angle information to the detector; secondly, the angle-of-arrival information is taken into account on the basis of particle filtering, which can dynamically shrink the source searching area and improve the searching efficiency; lastly, the angle-of-arrival-guided robot attitude adjustment is adopted in the path planning of the autonomous source searching, which can enhance the flexibility of the robot in searching for the source. Simulation experiments prove that this method can work correctly and effectively, and tests using radioactive sources further verify the practicality of this method for multi-source search.
Subjects: Psychology >> Other Disciplines of Psychology submitted time 2024-05-27
Abstract： Depression-induced suicide is the second leading cause of death among adolescents, and prolonged mobile phone usage has emerged as a significant public health concern with this demographic. However, the relationship between the duration of mobile phone usage and the manifestation of depressive symptoms in adolescents remains unexplored. This study aims to investigate the characteristics, evolution patterns, and gender differences in depressive symptoms among adolescents based on varying durations of mobile phone usage, as well as to provide new strategies for the prevention and control of depression among them. A large-scale survey was conducted on 167,728 adolescents in Nanchong City using the 20-item Center for Epidemiological Studies Depression Scale (CES-D). Mobile phone usage was categorized as follows: Non-use on rest days (T1), usage on rest days for ≤3 hours per day (T2), and usage on rest days for >3 hours per day (T3). The collected data were analyzed using R software (version 4.3.2) and its network analysis packages. The study compared the differences in the depressive symptom networks among adolescents with varying duration of mobile phone usage on rest days, as well as the differences between genders for the same mobile phone usage duration. Network analysis revealed that the longer the duration of mobile phone usage among adolescents, the more severe the symptoms of depression. Among the symptoms of depression in adolescents, ’sadness’, ’sense of failure’, ’lack of pleasure’, and ’lack of happiness’ have a higher degree of strength centrality. We performed a comparative analysis of the depression symptom network under different mobile phone usage durations on rest days. There were no significant differences in global strength and network edges between the T2 and T1 networks, but a significant difference in network structure, with the strength centrality of one symptom being significantly different. The T3 vs. T1 network showed significant differences in global strength, network structure, and network edges, with 32 edges showing significant differences and the strength centrality of 8 symptoms being significantly different. The T3 vs. T2 network also showed significant differences in global strength, network structure, and network edges, with 19 edges showing significant differences and the strength centrality of 10 symptoms being significantly different. Additionally, we also revealed the comparative analysis of the depression symptom network among different genders with the same mobile phone usage duration on rest days. Under the T1 condition, there were no significant differences in network structure and network edges between the female and male groups, but a significant difference in global strength, with the strength centrality of one symptom being significantly different. Under the T2 and T3 conditions, there were significant differences in global strength, network structure, and network edges between female and male groups. Under the T2 condition, there were significant differences in 25 edges and the strength centrality of 8 symptoms. Under the T3 condition, there were significant differences in 15 edges and the strength centrality of 5 symptoms. The current study indicated that the characteristics and evolution patterns of depressive symptoms in adolescents varied according to the duration of mobile phone usage, and notable gender differences. This study, based on the evolution patterns of various depressive symptoms, innovatively proposes four evolution patterns of depressive symptoms. This findings provide new strategies for the prevention and control of adolescent depression.
Peer Review Status:Awaiting Review
Subjects: Materials Science >> Materials Science (General) submitted time 2024-05-27
Abstract： Manufacturing hydrogels with identical electrochemical properties are typically riddled with unresolved inquiries and challenges. Here, we utilized ultra-light graphene flakes to trace the influence of convection phenomena during reactions on hydrogels’ formation and structural non-uniformity, elucidating its mechanisms. Furthermore, we confirmed that an external electric field induced the orientation of functional groups of hydrogels along the direction of this field, revealing the mechanism of its influence on the structural non-uniformity and electrochemical properties of hydrogels. Additionally, we discovered that ion diffusion was Stumbling-to-Fetters by the functional groups on the polymer chains within the hydrogel, unveiling this mechanism and developing the Virginia Creeper (VC) model for hydrogels. We demonstrated the scalability and application of the VC model. Furthermore, we proposed a molecular-ion diffusion and current decay equation to describe the electrochemical properties of hydrogels. As an application of the VC model, we developed a bionic cardiovascular system and proved its potential to seamlessly interface with living organisms and generate bio-like bioelectricity. Our findings provide novel insights into triboelectricity and guidance for producing hydrogels with identical electrochemical properties, and offer a new pathway for bioelectric generation and the design of new hydrogel devices.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Acute ischemic stroke（AIS）is characterized by high rates of disability，mortality，and recurrence，posing a significant burden on patients and society. In the era of big data，predictive models are increasingly used in patient diagnosis，treatment decisions，prognosis management，and healthcare resource allocation，highlighting their growing importance. Machine learning methods have become a crucial tool for predicting the prognosis of AIS patients and have been widely applied. This review explores recent advancements in the study of AIS prognosis prediction，focusing on machine learning methods. It discusses current issues and challenges faced by machine learning models，aiming to provide new insights and references for methods of early assessment and prediction of prognosis outcomes in AIS patients.
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background Previous studies have found that inter-arm blood pressure difference（IAD）and mild cognitive impairment（MCI）are both associated with cardiovascular risk factors，but it is unclear whether there is an association between IAD and MCI. Objective To explore the relationship between IAD and MCI in rural elderly persons and to provide a scientific basis for clarifying the mechanisms of cognitive decline in elderly persons. Methods From July to August 2019，the rural elderly residents aged 60 years and older were selected using the multi-stage cluster sampling method from 5 townships in 2 counties（districts）of Guizhou Province，and questionnaire surveys，general physical examinations，cognitive function assessments，and bilateral arm blood pressure measurements were carried out among them. Cognitive function was evaluated using the Mini-Mental State Examination（MMSE） scale，and activities of daily living were assessed using the Activities of Daily Living（ADL） scale. Spearman rank correlation analysis and binary logistic regression model were used to investigate the association between IAD and MCI in the elderly persons. Results A total of 1 795 questionnaires were distributed，and data from 1 088 participants were finally included in the study by excluding subjects with incomplete information on the questionnaires，those who did not undergo blood pressure measurements，and those who did not undergo blood tests. Among the 1 088 rural elderly residents，138 patients（12.68%）with MCI，99 patients（9.10%）with systolic inter-arm blood pressure difference（sIAD） ≥ 10 mmHg，and 80 patients（7.35%）with diastolic inter-arm blood pressure difference（dIAD） ≥ 10 mmHg were detected. Individuals with IAD ≥ 10 mmHg had a higher prevalence of MCI and lower MMSE scores，orientation scores，language scores，and delayed recall scores compared to those with IAD <10 mmHg （P<0.05）. The results of correlation analysis showed that the sIAD was significantly negatively associated with the total MMSE score （rs=-0.094），orientation score （rs=-0.082），verbal ability score （rs=-0.065） and delayed recall score （rs=-0.104）；and the dIAD was significantly negatively associated with the total MMSE score （rs=-0.080），orientation score （rs=-0.094），and attentional calculation score （rs=-0.063）（all P<0.05）. Multivariate logistic regression analysis showed that the risk of MCI increased by 8.80% for each 1 mmHg increase in sIAD （OR=1.088，95%CI=1.046-1.131；P<0.001）；sIAD ≥ 10 mmHg （OR=2.169，95%CI=1.262-3.728；P<0.05） and dIAD ≥ 10 mmHg （OR=1.926，95%CI=1.047-3.542；P<0.05） were the influencing factors for the occurrence of MCI in the elderly. Conclusion The prevalence of MCI in rural elderly was 12.68%，and their elevated IAD was associated with an increased risk of MCI. And the risk of MCI was higher in elderly with IAD ≥ 10 mmHg than in those with IAD <10 mmHg.
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